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Moreover, a longitudinal study of 360 older adults (60 years or older) in Germany found that vitamin B 6 status, measured by serum PLP concentration, did not decline over an 18-year period, although more than one-third of participants had PLP concentrations less than 30 nmol/L (133)

Figure 2 3.2

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Pre-Clinical In Vitro and In Vivo Studies The therapeutic use of ALA in the treatment of NP was first proposed in the end of the 1950s [72]
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