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Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine 27

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This condition may be considered when perioperative refractory hypotension develops after cardiovascular or transplantation surgery

Inhibitors targeting enzymes such as adenosine phosphate transferase, non-ribosomal peptide synthase (NRPS), polyketide synthase, and NRPS-independent siderophore synthases impair microbial iron uptake and enhance host-mediated clearance (Petrik et al., 2012