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Description
TET2 is involved in differentiation of haematopoietic stem cells (HSCs)
An imbalance in this circuit can cause an increase in sensitivity to chemicals and food, as well as brain fog
In the mitochondria the acetyl-CoA is diverted into the ketone synthesis pathway producing acetoacetate which, due to the elevated NADH levels, is preferentially converted to -hydroxybutyrate
A recent report revealed that ferroptosis inducers, such as RSL3 and erastin, induced the ASK1-p38 MAPK pathway activation downstream of lipid ROS in A549 cells [43]
