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SARS-CoV-2 infection in some patients causes acute respiratory distress syndrome (ARDS), and TGF- is an essential factor that accumulates in the lavage fluid of patients with ARDS and can be used as a therapeutic target [7, 9,10,11]

doi: 10.3389/fnins.2019.00005 8

Disruption of gut mucosal integrity and barrier dysfunction results in increased permeability to allergens, toxins and pathogens, leading to immunological stress response and inflammation (28, 34)

We also found associations between Cd RRG with the genes CAX3 and PDR3 , two linked adjacent genes, and leaf accumulation of Hg associated with the genes NRAMP6 and CAX9