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Description
Among the various pathways affected by visfatin are oxidative stress response, apoptosis, lipid and glucose metabolism, IR, and inflammation, which likely play a role in the pathogenesis of MASLD

While no studies show cancer causation, those with a history of cancer should avoid these compounds due to IGF-1s mitogenic properties

Future studies using chronic or aged animal models will be essential to evaluate prolonged efficacy, dose tolerance, and systemic safety, including potential effects on organ function and histopathology

10.1186/1479-5876-11-24 95 ZhangM.ZhangY.XiaoD.ZhangJ.WangX.GuanF.et al (2020)
