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This process of collagen synthesis by fibroblasts may be critical to the overall restoration and healing of damaged tissues
Some of the released molecules, referred to as damage-associated molecular patterns (DAMPs) like heme and its derivatives, ATP, heat shock protein (HSP70), or interleukin-33 (IL-33), are capable of triggering the immune response, amplifying inflammation [62, 63]
doi: 10.1007/s11064-017-2288-7
doi: 10.1056/NEJMra1208937
