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Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine

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They lie just outside the epithelial cells that make up blood vessels and in the areas surrounding the nerves and myocytes

Participants were intravenously given either 150 mg/kg of NAC or 5% dextrose (placebo) in water by intravenous infusion