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The diagnostic value may be both positive and negative, the positive diagnostic value being the probability that a subject classified as positive by the test is actually ill, and the negative diagnostic value being the probability that subjects negative at the test are actually healthy individuals

Acknowledgements This work was supported by the National Natural Science Foundation of China (21102182), the Natural Science Foundation of Jiangsu Province (BK2012760, China), Fundamental Research Funds for the Central Universities (2632018ZD09, China), and Excellent Science and Technology Innovation Team of Jiangsu Province Universities in 2015 (China)

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29 The junctional protein JAM-A is also involved in the barrier function, and decreased JAM-A expression has been reported in IBDs