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Differences among cell types in NAD(+) compartmentalization: a comparison of neurons, astrocytes, and cardiac myocytes

The success of this approach in modulating both energy metabolism and epigenetic regulation suggests that other metabolic nodes may offer similar opportunities for dual-pathway intervention
doi: 10.1177/014860719902300509

These results suggest that sublingual and oral B12 supplementation may serve as viable alternatives to IM injections, particularly in clinical settings where frequent intramuscular administration is impractical or resource intensive
