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In addition, an in vivo shRNA library screen and validation using CRISPR induced gene deletion revealed that the loss of several p53-regulated DNA repair genes can markedly accelerate c-MYC-driven lymphomagenesis and the removal of Mlh1 , a key gene involved in MMR, can even on its own promote spontaneous tumour development [58]
The lumbar region (vertebrae L1-L5) features vertebrae that are much larger to absorb the stress of lifting and carrying heavy objects
They belong in research settings for a reason
Degenerative disorders of the thoracic and lumbar spine
