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Mitochondrial dysfunction has been proved to be associated with aging and disease development [154], and it was seen that transient increase in the mechanism of autophagy represents a compensatory response to this dysfunction [155]

Drug Metabolism and pharmacokinetics of antisense oligonucleotide therapeutics: typical profiles, evaluation approaches, and points to consider compared with small molecule drugs

PMID: 37744291 49

[DOI] [PubMed] [Google Scholar] 176.Kean W.F., Hart L., Buchanan W.W
