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Thats because meth causes such intense, pleasurable effects that when it wears off, individuals feel empty
doi: 10.1038/nrc3483
Rationale and design of REDUCE-IT: Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial
A Phase 2 study published in The New England Journal of Medicine (Jastreboff et al., 2023) reported substantial weight reduction in participants with obesity
