nadph dependent glutathione reductase Pathways The NADPH Link between the

In brief, the peak area of the metabolite was normalized to the peak area of an isotopically labelled internal standard with similar elution time, both in samples from culture medium and external standard library dilutions

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More recent findings suggest that NAC corrects the alterations in glutamate homeostasis associated with drug addiction by inducing GLT1, a glial transporter that clears extracellular glutamate and inhibits the activation of extrasynaptic receptors that are involved in the induction and expression of maladaptive synaptic plasticity, such as mGlu5 receptors [117]

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