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Neuron 43 , 527537 (2004)
The authors showed that chronic (8 week) treatment of benfotiamine improved spatial memory, and reduced amyloid plaque and phosphorylated tau levels in amyloid precursor protein (APP)/presenilin-1 transgenic mice
Once NAC is inside the cells it is rapidly hydrolyzed, then cytosolic acylase I deacetylates NAC ( Figure 2Antioxidant activity of NAC.Increasing reactive oxygen species (ROS) depletes the antioxidant enzymes in the cells
Polyphyllin VII (PPVII), a pennogenin isolated from the rhizomes of Paris polyphylla, was detected to suppress the growth of gastric cancer by inducing autophagy-mediated ferroptosis [122]
