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Only supportive care is currently the mainstay of ALI/ARDS treatment, and no clinically approved pharmacotherapy is available, although many drug candidates demonstrated significant efficacy in preclinical tests and early phases of clinical trials

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Specifically, most metazoans use the transsulfuration pathway to move the reduced S from Hcy to Cys, thereby using the Met cycle to feed the production of Cys and Cys-derived products, including GSH, taurine, and CoA

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The group I GRXs undertake oxidoreductase functions and are found in most organisms

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doi: 10.1007/s00535-017-1415-1

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