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PLoS One 4:e5156 Hanspal M, Dua M, Takakuwa Y, Chishti AH, Mizuno A (2002) Plasmodium falciparum cysteine protease falcipain-2 cleaves erythrocyte membrane skeletal proteins at late stages of parasite development

During this process, PLA particles were colonized by gut microbes, forming surface biofilms and increasing pullulanase activityan enzyme that degrades branched polysaccharidesthe authors suggested this may have broken down PLA into smaller carbon-rich molecules, potentially supporting Bifidobacterium growth, without triggering pathogenic overgrowth or inflammatory responses (Jimnez-Arroyo et al., 2023)

Nature 165, 921922

Sakamoto A, Nishimura Y, Ono H, Sakura N