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Pale or yellow skin A lack of B12 can limit the production of red blood cells, which may cause the skin to look pale or have a hint of yellow

Moosavi M

In Microbiologically Influenced Corrosion in the Upstream Oil and Gas Industry , 379392 (2017)

However, a few contrary reports suggest that IL-6 deficient mice lacking the expression of cytoprotective heat shock proteins (HSPs) would be more susceptible to APAP hepatotoxicity [193]
