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Supporting this hypothesis, we observed the activation of GCN2, a key regulator of amino acid deficiency, but not PERK upon erastin treatment or cystine starvation in both MDA-MB-231 and Panc-1 cells (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 186.Zhao G., Ho W., Chu J., Xiong X., Hu B., Yiadom K.O., Xu X., Zhang X.-Q
