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Sono-driven STING activation using semiconducting polymeric nanoagonists for precision sonoimmunotherapy of head and neck squamous cell carcinoma

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To overcome this limitation, research efforts have been devoted to the development of therapeutic agents with biological mechanisms of action that are independent of the oxygen concentration

For instance, deoxycholic acid (DCA) and lithocholic acid (LCA), produced by 7-dehydroxylating bacteria like Clostridium scindens ( 67, 74), often promote an immunosuppressive TIME