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Reduced hepatic bilirubin clearance can be due to defective (i) unconjugated bilirubin uptake and intrahepatic storage, (ii) conjugation of glucuronic acid to bilirubin (e.g., Gilbert syndrome, CriglerNajjar syndrome, LuceyDriscoll syndrome, breast milk jaundice), (iii) bilirubin excretion into bile (DubinJohnson syndrome), or (iv) conjugated bilirubin re-uptake (Rotor syndrome)

[DOI] [PMC free article] [PubMed] [Google Scholar] Miric DJ, Kisic BM, Filipovic-Danic S, Grbic R, Dragojevic I, Miric MB, Puhalo-Sladoje D

Aquaculture 431, 111117

NO is a hydrophobic gas molecule with a high diffusion coefficient but a short life-time mainly due to its rapid reaction with oxygen and multiple cellular components