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Conditional knockout of p65 in macrophages impairs GYY4137 protective effects against OA progression To examine the role of the NF-kB signaling in mediating GYY4137 protective effects on osteoarthritis progression in vivo, we generated p65 f/f LysM-CreER T2 conditional knockout mice as described in Fig
Hmedeh C, Ghazeeri G, Tewfik I
doi: 10.1046/j.1365-2265.1996.722543.x
Researchers have administered this dosage safely for up to two weeks, based on available case reports
