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inducible NOS (also known as iNOS, type II, NOS-II, and NOS2), being the isoform which can be synthesized following induction by pro-inflammatory cytokines or endotoxin and endothelial NOS (also known as eNOS, type III, NOS-III, and NOS-3), being the isoform expressed in endothelial cells (Murphy et al., 1993