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Metabolic gene polymorphism frequencies in control populations

Briefly, a relationship exists between the frequency of the variant in the library (as measured by read count) and the magnitude of noise potentially affecting the measurement

Similar findings were also reported in PMA-stimulated mouse and human neutrophils where inhibition of G6PD significantly impaired their ability to undergo oxidative burst (64)

Because mitochondrial ROS have been implicated in other forms of cell death, specifically apoptosis, we co-treated cells with a mitochondrial scavenger (SKQ1) and the apoptosis inducer staurosporine (STS)