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Because of this risk, your healthcare provider will probably recommend continued surveillance, just to be safe
Erastin-induced ferroptosis was reduced by the antioxidant trolox.7,82 Additional drugs shown to decrease erastin-induced ferroptosis include ebselen (glutathione peroxidase mimetic) and the MEK inhibitor U0126,7 as well as baicalein which suppressed erastin-mediated GPX-4 degradation in pancreatic cancer.84 Rosiglitazone has ACSL4 inhibitor y effect and prolongs survival in GPX4/ mice.31 While the drug is no longer available for clinical use for diabetes in Europe due to safety concerns, the short term and even single dose use needed in AKI may be safe

Thus, it is concerning that COVID-19-related inflammation may trigger or accelerate PD in patients at risk

This is one reason careful dosing remains important
