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The Surface expression of MHCI and Fas on tumor cells was first examined
497502, www.ncbi.nlm.nih.gov/pmc/articles/PMC2596047/#:~:text=Glutathione%20plays%20a%20key%20role.
However, the contrasting nature of the results observed, particularly regarding the effects on cardiovascular morbidity and mortality in observational versus intervention studies, suggests that further research is warranted to support the repurposing of methotrexate for cardiovascular prevention (Table 1)
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