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doi: 10.3389/fmicb.2025.1607824 35 DoukasP

Carozzi VA, Canta A, Chiorazzi A

Senescent mitochondria not only produce more ROS due to inefficient electron transport but also exhibit impaired iron-sulfur cluster biogenesis, leading to improper iron handling and accumulation within the mitochondria, thus creating a potent internal source of oxidative stress (106,107)
