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Unlike other carcinogenic exposures discussed in this chapter that require nuanced risk-benefit evaluation, tire and plastic singeing offers no legitimate trade-off: cleaner alternatives (LPG torches, clean wood fires) achieve identical processing outcomes at modest additional cost

Both metalloproteinase and plasmin play a role in matrix remodeling and the renewal of ECM

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Development of lymphoma, though very unusual, must be considered if there is growth or pain in the involved gland
