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Hot-spot effect is caused by the reverse bias when the cells connected in series or in parallel fail to work synchronously because of either intrinsic fault or extrinsic shading or soiling

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The overall treatment discontinuation rate is lower with cagrilintide (about 1%) compared to semaglutide (5-7%)

It is very important to note that these substances of abuse remain prohibited and athletes can still be given sanctions up to four years for presence of a substance of abuse if they cannot establish that its use was out-of-competition and unrelated to sport