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Mechanistic analysis revealed that quercetin activates the Keap1Nrf2 pathway, upregulates downstream antioxidant genes ( nrf2 , ho-1 , sod , cat ), and increases SOD and catalase (CAT) activity, thereby eliminating excessive reactive oxygen species (ROS) and malondialdehyde (MDA)
Thus, GHK-Cu exhibits antioxidant function in wounds by inhibiting ferritin iron release in damaged tissues, preventing inflammation and microbial infections [37]
Both compounds independently cause nausea, vomiting, diarrhea, and constipation - especially during dose increases
Ewert, D
