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The article concludes by highlighting the importance of Nrf2 activation in enhancing antioxidant defences, reducing chronic inflammation, and improving insulin sensitivity

It supports the bodys antioxidant defenses and helps support healthy liver cell function

Specifically, mutant KRAS elevates ROS levels derived from mitochondria, which in turn induces acinar cells to undergo metaplasia into ductal epithelium, ultimately leading to the development of pancreatic intraepithelial neoplasia (104)

C., et al., Full Endoscopic versus Open Discectomy for Sciatica: Randomised Controlled Noninferiority Trial, Bmj 376 (2022): e065846