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2021;372:n265
The epidemic dynamics of hepatitis C virus subtypes 4a and 4d in Saudi Arabia
doi: 10.1016/j.ejca.2020.12.021 140 AsciertoPASchadendorfDBerkingCAgarwalaSSvan HerpenCMQueiroloPet al
Here we demonstrate that the cellular metabolite flavin adenine dinucleotide (FAD) is used as a non-canonical initiating nucleotide by the viral RNA-dependent RNA polymerase, resulting in a 5-FAD cap on the HCV RNA
