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Lineage-specific (LS) genomic regions of pathogens are considered to be enriched with plant-induced genes, including those encoding secreted proteins (SPs) 5, 6

Metformin also disrupts the growth and metastasis of NSCLC by inhibiting the activity of the miR-381-YAP-Snail axis (70)

et al., 2023), Grapefruit PDEVs, on the other hand, significantly improved the ovarian microenvironment by regulating the expression of pro-inflammatory factors such as TNF- and IL-6 with their rich flavonoids (Wang et al., 2014)

Optimal use involves standardized extracts, typically providing 200-400 mg of silymarin daily, often divided into multiple doses