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Due to difficulties in estimating indirect costs in hospitals associated with a particular diagnosis or procedure, Health Quality Ontario normally defaults to a consideration of direct treatment costs only

While higher doses (particularly 54 mg) showed some increase in gastrointestinal-related events, these remained mild to moderate in severity and did not result in treatment discontinuation

Enhanced gut lining repair and long-term digestive health

The key is avoiding receptor desensitization by taking adequate breaks between cycles
