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Intrinsic factor deficiency, or "congenital pernicious anemia," is a rare autosomal recessive disorder characterized by the lack of gastric intrinsic factor in the presence of normal gastric acid secretion and mucosal cytology (ie, without gastritis) and in the absence of intrinsic factor antibodies found in the acquired form of pernicious anemia

Diagnosis of cobalamin malabsorption usually involves bloodwork to measure serum cobalamin levels and may include genetic tests, especially for informed breeding decisions

Some patients view these shots as a short-term boost, others as a maintenance therapy
