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Studies have also shown creatine supplementation can augment the effects of therapy, even without medication

Neurology 06, 510

Furthermore, due to its close interaction with NO-system, as NO acts as an endogenous cardioprotectant antifibrillatory factor [64,65] and BPC 157 has no proarrhytmic effect by itself, BPC 157 might counteract various arrhythmias, including those aggravated by NOS-blockade [66,67,68,69,70,71,72] (note, first communication was about the shortened duration of arrhythmias during hypoxia and the reoxygenation period in isolated guinea pig hearts [73])

For instance, NR supplementation in preclinical studies has been shown to reduce chemotherapy-induced peripheral neuropathy, inhibit cancer metastasis, and, in some cases, enhance tumor-suppressive effects. A brief summary of these findings can be found below in the Appendix in Table 1, illustrating that NAD+ metabolism is complex and may be protective under certain conditions
