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For instance, Ishikawa cells are prone to losing cellular phenotype (such as loss of hormone receptor expression), exhibiting genetic modifications during prolonged culture, and showing instability at microsatellite loci

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Donepezil, piracetam, vinpocetine or Ginkgo biloba co-administered with cannabis (20 mg/kg) improved performance resulting in significantly shorter latencies to find the hidden platform than the cannabis (20 mg/kg) only-treated group (Figure 5B(Fig