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[10] [11] A phase II clinical trial on the efficacy and safety of meldonium for acute ischemic stroke was completed in August 2013 and the studies showed that meldonium is as effective and safe as cinepazide injection

53,57,58 A meta-analysis of six randomized controlled trials with a total of 355 participants found myo-inositol was comparable to metformin with regard to its effects on fasting insulin and insulin sensitivity, testosterone, sex hormone binding globulin (SHBG), and body mass index (BMI) (a measure of body weight status) in women with PCOS, while metformin treatment carried a higher risk of adverse effects

doi: 10.1155/2017/4314025

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