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Mitophagy in macrophages, as a selective autophagy mechanism, may also influence macrophage differentiation through its impact on ROS levels
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doi: 10.2174/1574892816666210607100239 107 YangYXiongGShiHPengYLiuJJiangYet al

The vacuolar membrane-localized TgMTP1 of hyperaccumulator confers tolerance to a broad spectrum of heavy metals including Ni, Cd, Zn, and Co, and complements the metal sensitivity of the yeast / mutant strains (Persans et al., 2001), and could particularly increase zinc tolerance by initiating a systemic Zn deficiency response including up-regulation of Zn transporter genes (, , and ) (Gustin et al., 2009)
