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Across multiple experimental settings, these agents demonstrate biologic activity involving angiogenesis, inflammatory modulation, fibroblast migration, and collagen remodeling
GHK-Cu works by signaling, not by accumulation
Wnt3a / double knockout mice, absence of these Wnt members from the dorsal neural tube during later stages of otocyst development results in severe vestibular defects, including a complete lack of utricle and saccule
