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However, recent years have seen the advent of innovative therapeutic stratagems encompassing gene therapy, small molecule pharmaceuticals, and cell-based interpositions, all of which imbue optimism for the development of more efficacious treatment alternatives for afflicted patients

[DOI] [PubMed] [Google Scholar] Vinceti M, Filippini T, Cilloni S, Bargellini A, Vergoni AV, Tsatsakis A, Ferrante M

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It is important to note that sphingosine and sphinganine analysis needs liquid chromatographic techniques (LC/MS, LC/MS-MS), and further possible candidate compounds need much more sensitive detection (LC-TOF or LC-qTOF)