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A systematic review highlighted the efficacy of AI algorithms in sperm selection, reporting that convolutional neural networks (CNNs) achieved up to 90.73% accuracy in automating morphological classification of sperm images (168, 169)

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We, therefore, selected a rare clinical model (secondary hypogonadism due to isolated LH deficiency), in which we may observe LH and testosterone deficiency associated with a normal or low-normal FSH secretion, and presence of spermatogenesis