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Since NF-kB also regulates RAGE expression, its overexpression causes more AGE binding and, therefore, it forms a feedback loop that activates the inflammatory pathway and the neuronal death (Guerrero et al., 2013)
Port Size(mm): 2
[DOI] [PubMed] [Google Scholar] 249.Pellicoro A, Ramachandran P, Iredale JP, Fallowfield JA
