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Low glutathione levels are found in people with lupus, rheumatoid arthritis (RA), Crohns disease (IBD), multiple sclerosis (MS), and psoriasis.[ref] Related articles: Lupus, Rheumatoid arthritis, IBD, MS, and psoriasis genes Cystic fibrosis: People with cystic fibrosis, which is a genetic disease caused by mutations in the CFTR gene, have frequent respiratory infections that cause lung inflammation and produce oxidative stress in the lungs, which depletes glutathione levels