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The issue of drug resistance could be prevented by combining gefitinib, a therapeutic drug for patients with NSCLC with EGFR mutations, and BCH, a SLC7A5 inhibitor that reduces the phosphorylation level of mTOR and its downstream molecules (93)

10.1002/anie.202414941

J Pharmacol Sci 108(4):439445 Al-Qahtani WH, Alshammari GM, Ajarem JS, Al-Zahrani AY, Alzuwaydi A, Eid R et al (2022) Isoliquiritigenin prevents Doxorubicin-induced hepatic damage in rats by upregulating and activating SIRT1

In principle, glutathione is present in the body mostly in reduced form, i.e
