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Description
Endogenous hGH is secreted in periodic bursts over a 24 hour period with great variability in burst frequency, amplitude and duration

Overstimulation risks include menstrual irregularity, cyst formation, or estrogen dominance

For example, in a multicenter observational retrospective study, statins were being used by 19.4% of the patients with various types of cancer following PD/PD-L1 therapy, and the baseline use of statins was independently related to an increased objective response rate (ORS), but not with progression-free survival (PFS) and overall survival (OS) (Cortellini et al., 2020)

doi: 10.1039/D1FO03077A
