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Beyond its classical metabolic role, research has found that DHODH can limit lipid peroxidation within mitochondria by maintaining its own mitochondrial CoQ/CoQH 2 redox pool, thereby independently suppressing ferroptosis (Mao et al., 2021

Interestingly, ADSCs can inhibit the proliferation and melanogenesis of epidermal melanocytes through an interleukin-6 (IL-6)-mediated mechanism 114 and through upregulation of TGF-1 43

We will describe here briefly what is understood regarding the signaling by HNE

Metabolites 7 (2), 14