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The five most upregulated genes in OPCs were HSPH1, CHORDC1, HSPA4L, PTGES3 and HSPA1A, while the five most downregulated genes were ROBO2, RYR2, TENM2, SYT1 and GALNTL6 (Fig

In contrast, TIGAR overexpression or treatment with Fer-1, a ferroptosis inhibitor, significantly increases NADPH, GPX4, and GSH levels, reduces GSSG expression, and attenuates neuronal ferroptosis and neurological impairment

In contrast, NFTs are made up of hyperphosphorylated tau protein and are formed within neuronal cell bodies and axons which can directly spread to other parts of the brain

Molecular Docking Studies of N-Acetyl Cysteine, Zinc Acetyl Cysteine and Niclosamide on SARS Cov 2 Protease and Its Comparison with Hydroxychloroquine