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GHK-Cu is a copper-complexed tripeptide (Glycine-Histidine-Lysine-Cu) naturally present in human plasma, saliva, and urine

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N.H.S.: UM1 CA186107, P01 CA87969, R01 CA49449, R01-CA67262, UM1 CA176726

Results Increased severity of liver injury and mortality of mice with hepsin deficiency during the early period after acetaminophen exposure To investigate the potential physiological role of endogenous hepsin in the early response to APAP-induced liver injury, we analyzed hepsin expression in wild-type mouse liver lysates following APAP treatment using western blotting (Fig