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Enhancing effectiveness, prolonging half-life in vivo, and developing biphasic therapeutic monoclonal antibodies, which may be broadly applicable to different combinations of target antigens are important objectives to be pursued

doi: 10.1126/science.1092385 49 ZhangDFrenettePS

It cannot enter most cells directly and therefore must be made available inside the cell from its three constituent amino acids:[..] Marine unicellular Cyanobacteria of the Synechococcus group occupy an important position at the base of the marine food web

The therapeutic window for systemic iron chelation in FRDA is notoriously narrow
