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De Novo Lipogenesis as a Source of Second Messengers in Adipocytes

These nonseroconverters include people on B-cell-depleting therapy or people with inborn errors of immunity, as these individuals are typically more susceptible to prolonged infection and higher rates of progression to severe disease [36, 37]

This process, known as paracrine signaling, allows exosomes to interact with cells in various ways - activating receptors on cell surfaces, merging with target cell membranes to release their cargo, or influencing the surrounding environment